Locally administrated perindopril improves healing in an ovariectomized rat tibial osteotomy model.

Angiotensin-converting enzyme inhibitors are widely prescribed to regulate blood pressure. High doses of orally administered perindopril have previously been shown to improve fracture healing in a mouse femur fracture model. In this study, perindopril was administered directly to the fracture area w...

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Bibliographic Details
Main Authors: Xiong Zhao, Zi-xiang Wu, Yang Zhang, Ming-xuan Gao, Ya-bo Yan, Peng-chong Cao, Yuan Zang, Wei Lei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302837?pdf=render