Differential stability of cell-free circulating microRNAs: implications for their utilization as biomarkers.

BACKGROUND: MicroRNAs circulating in the blood, stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles, are currently being evaluated as biomarkers. The consequences of their differential association with lipids/vesicles for their stability and use as biomark...

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Main Authors: Verena Köberle, Thomas Pleli, Christian Schmithals, Eduardo Augusto Alonso, Jörg Haupenthal, Halvard Bönig, Jan Peveling-Oberhag, Ricardo M Biondi, Stefan Zeuzem, Bernd Kronenberger, Oliver Waidmann, Albrecht Piiper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3779196?pdf=render