Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.
DNA double-strand breaks are repaired by multiple mechanisms that are roughly grouped into the categories of homology-directed repair and non-homologous end joining. End-joining repair can be further classified as either classical non-homologous end joining, which requires DNA ligase 4, or "alt...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-07-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2895639?pdf=render |