Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila.

DNA double-strand breaks are repaired by multiple mechanisms that are roughly grouped into the categories of homology-directed repair and non-homologous end joining. End-joining repair can be further classified as either classical non-homologous end joining, which requires DNA ligase 4, or "alt...

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Bibliographic Details
Main Authors: Sze Ham Chan, Amy Marie Yu, Mitch McVey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2895639?pdf=render