Relevance and therapeutic possibility of PTEN-long in renal cell carcinoma.

Relevance and therapeutic possibility of PTEN-long in renal cell carcinoma.

PTEN-Long is a translational variant of PTEN (Phosphatase and Tensin Homolog). Like PTEN, PTEN-Long is able to antagonize the PI3K-Akt pathway and inhibits tumor growth. In this study, we investigated the role PTEN-Long plays in the development and progression of clear cell renal cell carcinoma (ccR...

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Bibliographic Details
Main Authors: Hui Wang, Peng Zhang, Chunhua Lin, Qingxia Yu, Jitao Wu, Lin Wang, Yupeng Cui, Ke Wang, Zhenli Gao, Hong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4340966?pdf=render

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http://europepmc.org/articles/PMC4340966?pdf=render

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