ACT001 reduced the expression of programmed cell death protein ligand 1 in glioblastoma cells by inhibiting P65 phosphorylation

ACT001 reduced the expression of programmed cell death protein ligand 1 in glioblastoma cells by inhibiting P65 phosphorylation

Objective To investigate the anti⁃tumoral effect of ACT001, a novel antitumor compound, on the nuclear factor⁃κB (NF⁃κB) pathway and programmed cell death protein ligand 1 (PDL1) expression in U87 glioblastoma cell line. Methods We analyzed the correlation between the expression of P65 and PDL1, pat...

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Bibliographic Details
Main Authors: ZHANG Jin⁃hao, LIU Pei⁃dong, ZHANG Chen, LI Jia⁃bo, REN Xiao, CHEN Lu⁃lu, SUN Jin⁃zhang, WANG Xu⁃ya, ZHANG Liang, YANG Xue⁃jun
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2021-06-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
glioblastoma
sesquiterpenes
nf⁃kappa b
programmed cell death 1 receptor
ligands
cell proliferation
transfection
microscopy
fluorescence
immunoblotting
tumor cells
cultured
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/2350

Internet

http://www.cjcnn.org/index.php/cjcnn/article/view/2350

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