Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

The prolonged treatment of immunosuppressed (IS) individuals with anti-influenza monotherapies may lead to the emergence of drug-resistant variants. Herein, we evaluated oseltamivir and polymerase inhibitors combinations against influenza A/H3N2 infections in an IS mouse model. Mice were IS with cyc...

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Bibliographic Details
Main Authors: Zeineb Mhamdi, Hugues Fausther-Bovendo, Olus Uyar, Julie Carbonneau, Marie-Christine Venable, Yacine Abed, Gary Kobinger, Guy Boivin, Mariana Baz
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Microorganisms
Subjects:
influenza
H3N2
immunosuppression
combination therapy
oseltamivir
favipiravir
Online Access:https://www.mdpi.com/2076-2607/8/12/1968

Internet

https://www.mdpi.com/2076-2607/8/12/1968

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