Comparison of inbred mouse substrains reveals segregation of maladaptive fear phenotypes

Maladaptive fear, such as fear that is persistent or easily generalized to a nonthreatening stimuli, is associated with anxiety-related disorders in humans. In the laboratory, maladaptive fear can be modeled in rodents using Pavlovian fear conditioning. Recently, an inbred mouse strain known as 129...

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Bibliographic Details
Main Authors: Stephanie J Temme, Ryan Z Bell, Reciton ePahumi, Geoffrey G Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00282/full