Adaptation of Oxford Nanopore technology for hepatitis C whole genome sequencing and identification of within-host viral variants

Adaptation of Oxford Nanopore technology for hepatitis C whole genome sequencing and identification of within-host viral variants

Abstract Background Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advances in next generation sequencing. This limitation...

Full description

Bibliographic Details
Main Authors: Nasir Riaz, Preston Leung, Kirston Barton, Martin A. Smith, Shaun Carswell, Rowena Bull, Andrew R. Lloyd, Chaturaka Rodrigo
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Genomics
Subjects:
Hepatitis C virus
Third generation sequencing
Nano-Q
Haplotypes
Oxford Nanopore technology
Online Access:https://doi.org/10.1186/s12864-021-07460-1

Internet

https://doi.org/10.1186/s12864-021-07460-1

Similar Items