[PROVISIONAL] Protective effects of bark ethanolic extract from Spondias dulcis Forst F. against DNA damage induced by Benzo[a]pyrene and Cyclophosphamide

[PROVISIONAL] Protective effects of bark ethanolic extract from Spondias dulcis Forst F. against DNA damage induced by Benzo[a]pyrene and Cyclophosphamide

Abstract This study evaluated the genotoxicity, mutagenicity, antigenotoxicity antimutagenicity and effects on biochemical parameters of oxidative stress of the bark ethanolic extract from Spondias dulcis on mice. The extract was evaluated in the doses of 500, 1000 and 1500 mg/kg bw via gavage. To e...

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Bibliographic Details
Main Authors: Caroline de S. Araujo, Lorrane D. Brito, Marina O. Tarifa, Nayara J. Farah da Silva, Karoline S. Rodrigues, Dalita G. S. M. Cavalcante, Andressa S. Gomes, Marcos A. Zocoler, Eidi Yoshihara, Marjori L. Camparoto, Aldo E. Job, Leandra E. Kerche-Silva
Format: Article
Language:English
Published: Sociedade Brasileira de Genética
Series:Genetics and Molecular Biology
Subjects:
Comet assay
Micronucleus Test
Spondias dulcis
cytotoxicity
mutagenicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019005019102&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572019005019102&lng=en&tlng=en

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