2-Ketogluconic acid and pyrroloquinoline quinone secreting probiotic Escherichia coli Nissle 1917 as a dietary strategy against heavy metal induced damage in rats

Objective: The objective of this study was to develop genetically modified probiotic E. coli Nissle 1917 (EcN-23) slowly releasing 2-ketogluconic acid (2-KG) as a chelator and pyrroloquinoline quinone (PQQ) as an antioxidant against heavy metal induced damage. Methods: Male rats were exposed separat...

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Bibliographic Details
Main Authors: Ruma Raghuvanshi, Archana Chaudhari, G. Naresh Kumar
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617304760