2-Ketogluconic acid and pyrroloquinoline quinone secreting probiotic Escherichia coli Nissle 1917 as a dietary strategy against heavy metal induced damage in rats
Objective: The objective of this study was to develop genetically modified probiotic E. coli Nissle 1917 (EcN-23) slowly releasing 2-ketogluconic acid (2-KG) as a chelator and pyrroloquinoline quinone (PQQ) as an antioxidant against heavy metal induced damage. Methods: Male rats were exposed separat...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-10-01
|
Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464617304760 |