IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid ModelSummary

Background & Aims: Crohn’s disease is an inflammatory bowel disease that affects the ileum and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 are increased in Crohn’s disease and are associated with disrupted epithelial regeneration, little is known abou...

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Bibliographic Details
Main Authors: Bailey Zwarycz, Adam D. Gracz, Kristina R. Rivera, Ian A. Williamson, Leigh A. Samsa, Josh Starmer, Michael A. Daniele, Luisa Salter-Cid, Qihong Zhao, Scott T. Magness
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X18300948