Overexpression of DNA damage-induced 45 α gene contributes to esophageal squamous cell cancer by promoter hypomethylation

Overexpression of DNA damage-induced 45 α gene contributes to esophageal squamous cell cancer by promoter hypomethylation

<p>Abstract</p> <p>Background</p> <p>Environmental factors-induced dysfunction of esophageal squamous epithelium, including genomic DNA impairment and apoptosis, play an important role in the pathogenesis of esophageal squamous cell cancer. DNA damage-induced 45α (GADD4...

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Bibliographic Details
Main Authors: Wang Bao xiang, Yin Bang Liang, He Bin, Chen Chen, Zhao Ming, Zhang Wei xing, Xia Zhen Kun, Pan Yi zhi, Tang Jing qun, Zhou Xin min, Yin Ni
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Esophageal squamous cell cancer
GADD45α
DNA methylation
DNA damage
Online Access:http://www.jeccr.com/content/31/1/11

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http://www.jeccr.com/content/31/1/11

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