Transcriptomics based multi-dimensional characterization and drug screen in esophageal squamous cell carcinoma

Transcriptomics based multi-dimensional characterization and drug screen in esophageal squamous cell carcinoma

Background: Esophageal squamous cell carcinoma (ESCC) remains one of the deadly cancer types. Comprehensively dissecting the molecular characterization and the heterogeneity of ESCC paves the way for developing more promising therapeutics. Methods: Expression profiles of multiple ESCC datasets were...

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Bibliographic Details
Main Authors: Yin Li, Fengkai Xu, Fanghua Chen, Yiwei Chen, Di Ge, Shu Zhang, Chunlai Lu
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EBioMedicine
Subjects:
Esophageal squamous cell carcinoma
RNA-seq
ATAC-seq
Molecular classification
Tumor stroma
Drug repurposing
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003030

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http://www.sciencedirect.com/science/article/pii/S2352396421003030

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