Inhibition of STAT3 signaling and induction of SHP1 mediate antiangiogenic and antitumor activities of ergosterol peroxide in U266 multiple myeloma cells

<p>Abstract</p> <p>Background</p> <p>Ergosterol peroxide (EP) derived from edible mushroom has been shown to exert anti-tumor activity in several cancer cells. In the present study, anti-angiogenic activity of EP was investigated with the underlying molecular mechanisms...

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Bibliographic Details
Main Authors: Rhee Yun-Hee, Jeong Soo-Jin, Lee Hyo-Jeong, Lee Hyo-Jung, Koh Wonil, Jung Ji, Kim Sun-Hee, Sung-Hoon Kim
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/12/28