Sequence-based information-theoretic features for gene essentiality prediction

Abstract Background Identification of essential genes is not only useful for our understanding of the minimal gene set required for cellular life but also aids the identification of novel drug targets in pathogens. In this work, we present a simple and effective gene essentiality prediction method u...

Full description

Bibliographic Details
Main Authors: Dawit Nigatu, Patrick Sobetzko, Malik Yousef, Werner Henkel
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1884-5