Genetic and pharmacological inhibition of acid ceramidase prevents asymmetric cell division by neosis[S]

Radiation treatment failure or relapse after initial response to chemotherapy presents significant clinical challenges in cancer patients. Escape from initial courses of treatment can involve reactivation of embryonic developmental stages, with the formation of polynuclear giant cancer cells (PGCCs)...

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Bibliographic Details
Main Authors: Shai White-Gilbertson, Ping Lu, James S. Norris, Christina Voelkel-Johnson
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520310555