PROTECTIVE ROLE OF SYLIMARIN ON METHOTREXATE INDUCED HEPATO-NEPHROTOXICITY IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Abstract Background:ALL is the most common childhood malignancy. ALL are treated with methotrexate (MTX) based chemotherapy protocols. MTX can cause unpredictable serious hepato-renal side effects. Sylimarin has antioxidant and anti-inflammatory activities, membrane stabilizing effect,stimulate tiss...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2016-09-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/2625 |