Synthesis of Aminoglycoside-2′-O-Methyl Oligoribonucleotide Fusions

Phosphoramidite building blocks of ribostamycin (3 and 4), that may be incorporated at any position of the oligonucleotide sequence, were synthesized. The building blocks, together with a previously described neomycin-modified solid support, were applied for the preparation of aminoglycoside-2′-O-me...

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Bibliographic Details
Main Authors: Lotta Granqvist, Andrzej Kraszewski, Ville Tähtinen, Pasi Virta
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/5/760