Physical activity and environmental enrichment regulate the generation of neural precursors in the adult mouse substantia nigra in a dopamine-dependent manner

Physical activity and environmental enrichment regulate the generation of neural precursors in the adult mouse substantia nigra in a dopamine-dependent manner

<p>Abstract</p> <p>Background</p> <p>Parkinson’s disease is characterized by a continuous loss of neurons within the substantia nigra (SN) leading to a depletion of dopamine. Within the adult SN as a non-neurogenic region, cells with mainly oligodendrocytic precursor ch...

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Bibliographic Details
Main Authors: Klaissle Philipp, Lesemann Anne, Huehnchen Petra, Hermann Andreas, Storch Alexander, Steiner Barbara
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Neuroscience
Subjects:
Physical activity
Environmental enrichment
Dopamine
NG2
Oligodendrocytes
Substantia nigra
Online Access:http://www.biomedcentral.com/1471-2202/13/132

Internet

http://www.biomedcentral.com/1471-2202/13/132

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