EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts

EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts

<p>Abstract</p> <p>Background</p> <p>Fourteen-membered ring macrolides have been effective in reducing chronic airway inflammation and also preventing lung injury and fibrosis in bleomycin-challenged mice via anti-inflammatory effects. EM703 is a new derivative of eryth...

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Main Authors: Inagaki Hirofumi, Hirata Yukiyo, Shimizu Takako, Sunazuka Toshiaki, Matsuda Kuniko, Abe Shinji, Usuki Jiro, Azuma Arata, Li Ying Ji, Kawada Tomoyuki, Takahashi Satoru, Kudoh Shoji, Omura Satoshi
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/7/1/16

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http://respiratory-research.com/content/7/1/16

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