Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

<p>Abstract</p> <p>Background</p> <p>Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. An animal model of chondrosarcoma has been...

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Bibliographic Details
Main Authors: Hamm Christopher A, Stevens Jeff W, Xie Hehuang, Vanin Elio F, Morcuende Jose A, Abdulkawy Hakeem, Seftor Elisabeth A, Sredni Simone T, Bischof Jared M, Wang Deli, Malchenko Sergey, de Fatima Bonaldo Maria, Casavant Thomas L, Hendrix Mary JC, Soares Marcelo B
Format: Article
Language:English
Published: BMC 2010-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/471

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http://www.biomedcentral.com/1471-2407/10/471

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