Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation
Alzheimer’s disease is a neuropathological condition with abnormal accumulation of extracellular Amyloid-β plaques and intracellular neurofibrillary tangles of Microtubule-associated protein Tau (Tau) in the brain. In pathological conditions, Tau undergoes post-translational modifications such as hy...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-12-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1177/1759091420981204 |