Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling

Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling

Abstract Background Work-place exposure to silica dust may lead to progressive lung inflammation culminating in the development of silicosis, an irreversible condition that can be complicated by onset of pulmonary hypertension (PH). The molecular mechanisms leading to the development of PH and lung...

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Bibliographic Details
Main Authors: Igor N. Zelko, Jianxin Zhu, Jesse Roman
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Respiratory Research
Subjects:
Oxidative stress
Transcription
Expression
Crystalline silica
Pulmonary hypertension
Lung fibrosis
Online Access:http://link.springer.com/article/10.1186/s12931-018-0933-6

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http://link.springer.com/article/10.1186/s12931-018-0933-6

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