Breast cancer stem cell-like cells are more sensitive to ionizing radiation than non-stem cells: role of ATM.

There are contradictory observations about the different radiosensitivities of cancer stem cells and cancer non-stem cells. To resolve these contradictory observations, we studied radiosensitivities by employing breast cancer stem cell (CSC)-like MDA-MB231 and MDA-MB453 cells as well as their corres...

Full description

Bibliographic Details
Main Authors: Seog-Young Kim, Juong G Rhee, Xinxin Song, Edward V Prochownik, Douglas R Spitz, Yong J Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3503893?pdf=render