Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-κB signaling in prostate cancer cells in vitro and in vivo.

Previously, we reported that retigeric acid B (RB), a natural pentacyclic triterpenic acid isolated from lichen, inhibited cell growth and induced apoptosis in androgen-independent prostate cancer (PCa) cells. However, the mechanism of action of RB remains unclear. In this study, we found that using...

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Bibliographic Details
Main Authors: Yong-Qing Liu, Xiao-Yan Hu, Tao Lu, Yan-Na Cheng, Charles Y F Young, Hui-Qing Yuan, Hong-Xiang Lou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3362538?pdf=render