CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution

Our structural understanding of class A penicillin binding proteins is incomplete due to the difficulty in their crystallization and the complexity of their substrates. Here, authors determine the structure of the 83 kDa class A PBP from Escherichia coli, PBP1b, using cryogenic electron microscopy a...

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Bibliographic Details
Main Authors: Nathanael A. Caveney, Sean D. Workman, Rui Yan, Claire E. Atkinson, Zhiheng Yu, Natalie C. J. Strynadka
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23063-6