Network-based regularization for high dimensional SNP data in the case–control study of Type 2 diabetes

Network-based regularization for high dimensional SNP data in the case–control study of Type 2 diabetes

Abstract Background Over the past decades, the prevalence of type 2 diabetes mellitus (T2D) has been steadily increasing around the world. Despite large efforts devoted to better understand the genetic basis of the disease, the identified susceptibility loci can only account for a small portion of t...

Full description

Bibliographic Details
Main Authors: Jie Ren, Tao He, Ye Li, Sai Liu, Yinhao Du, Yu Jiang, Cen Wu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genetics
Subjects:
Case–control association study
Network-based regularization
Regularized logistic regression
Type 2 diabetes
Variable selection
Online Access:http://link.springer.com/article/10.1186/s12863-017-0495-5

Internet

http://link.springer.com/article/10.1186/s12863-017-0495-5

Similar Items