Mathematical Modeling of Growth and Paclitaxel Biosynthesis in Corylus avellana Cell Culture Responding to Fungal Elicitors Using Multilayer Perceptron-Genetic Algorithm

Mathematical Modeling of Growth and Paclitaxel Biosynthesis in Corylus avellana Cell Culture Responding to Fungal Elicitors Using Multilayer Perceptron-Genetic Algorithm

Paclitaxel is the top-selling anticancer medicine in the world. In vitro culture of Corylus avellana has been made known as a promising and inexpensive strategy for producing paclitaxel. Fungal elicitors have been named as the most efficient strategy for enhancing the biosynthesis of secondary metab...

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Bibliographic Details
Main Authors: Mina Salehi, Siamak Farhadi, Ahmad Moieni, Naser Safaie, Hamed Ahmadi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Plant Science
Subjects:
secondary metabolite
endophytic fungus
cell extract
culture filtrate
artificial neural network
Online Access:https://www.frontiersin.org/article/10.3389/fpls.2020.01148/full

Internet

https://www.frontiersin.org/article/10.3389/fpls.2020.01148/full

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