Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload

Pathological cardiac remodeling during heart failure is associated with higher levels of lipid peroxidation products and lower abundance of several aldehyde detoxification enzymes, including aldehyde dehydrogenase 2 (ALDH2). An emerging idea that could explain these findings concerns the role of ele...

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Bibliographic Details
Main Authors: Sujith Dassanayaka, Yuting Zheng, Andrew A. Gibb, Timothy D. Cummins, Lindsey A. McNally, Kenneth R. Brittian, Ganapathy Jagatheesan, Timothy N. Audam, Bethany W. Long, Robert E. Brainard, Steven P. Jones, Bradford G. Hill
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718304117

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http://www.sciencedirect.com/science/article/pii/S2213231718304117

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