Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats

Impaired Activity of Ryanodine Receptors Contributes to Calcium Mishandling in Cardiomyocytes of Metabolic Syndrome Rats

Metabolic syndrome (MetS) has become a global epidemic. MetS is a serious health problem because of its related cardiovascular complications, which include hypertension and delayed heart rate recovery after exercise. The molecular bases of cardiac dysfunction in MetS are still under scrutiny and may...

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Bibliographic Details
Main Authors: Gaudencio Fernández-Miranda, Tatiana Romero-Garcia, Tarín P. Barrera-Lechuga, Martha Mercado-Morales, Angélica Rueda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Physiology
Subjects:
ryanodine receptor
calcium sparks
ryanodine binding
SERCA pump
cardiomyocytes
calcium mishandling
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00520/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00520/full

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