The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells.

The LIM-only protein FHL2, also known as DRAL or SLIM3, has a function in fine-tuning multiple physiological processes. FHL2 is expressed in the vessel wall in smooth muscle cells (SMCs) and endothelial cells and conflicting data have been reported on the regulatory function of FHL2 in SMC phenotype...

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Main Authors: Kondababu Kurakula, Mariska Vos, Iker Otermin Rubio, Goran Marinković, Reinhard Buettner, Lukas C Heukamp, Jan Stap, Vivian de Waard, Claudia M van Tiel, Carlie J M de Vries
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24736599/?tool=EBI