Intrathecal 99mTc‐DTPA imaging of molecular passage from lumbar cerebrospinal fluid to brain and periphery in humans

Abstract Introduction Cerebrospinal fluid (CSF) molecular exchange with brain interstitial fluid (ISF) and periphery is implicated in neurological disorders but needs better quantitative clinical assessment approaches. Methods Following intrathecal (ITH) dosing via lumbar puncture, Technetium‐99 m (...

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Bibliographic Details
Main Authors: Ajay Verma, Jacob Y. Hesterman, J. Levi Chazen, Robert Holt, Patrick Connolly, Laura Horky, Shankar Vallabhajosula, P. David Mozley
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Online Access:https://doi.org/10.1002/dad2.12030