Polycomb Factor PHF19 Controls Cell Growth and Differentiation Toward Erythroid Pathway in Chronic Myeloid Leukemia Cells

Polycomb Factor PHF19 Controls Cell Growth and Differentiation Toward Erythroid Pathway in Chronic Myeloid Leukemia Cells

Polycomb group (PcG) of proteins are a group of highly conserved epigenetic regulators involved in many biological functions, such as embryonic development, cell proliferation, and adult stem cell determination. PHD finger protein 19 (PHF19) is an associated factor of Polycomb repressor complex 2 (P...

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Bibliographic Details
Main Authors: Marc García-Montolio, Cecilia Ballaré, Enrique Blanco, Arantxa Gutiérrez, Sergi Aranda, Antonio Gómez, Chung H. Kok, David T. Yeung, Timothy P. Hughes, Pedro Vizán, Luciano Di Croce
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chronic myeloid leukemia
polycomb
PHF19
epigenetics
erythroid differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.655201/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.655201/full

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