HIF-1α Induces Multidrug Resistance in Gastric Cancer Cells by Inducing MiR-27a.

This study aimed to determine the correlation between HIF-1α and miR-27a expression and to evaluate the effect of inhibition of HIF-1α expression on miR-27a expression and drug resistance in gastric cancer (GC). In the present study, real time-PCR and Western blot were performed to detect the expres...

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Bibliographic Details
Main Authors: Qun Zhao, Yong Li, Bi-Bo Tan, Li-Qiao Fan, Pei-Gang Yang, Yuan Tian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546344?pdf=render