Functional Role of p53 in the Regulation of Chemical-Induced Oxidative Stress

The nuclear transcription factor p53, discovered in 1979, has a broad range of biological functions, primarily the regulation of apoptosis, the cell cycle, and DNA repair. In addition to these canonical functions, a growing body of evidence suggests that p53 plays an important role in regulating int...

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Bibliographic Details
Main Authors: Xiaoyi Liu, Lihong Fan, Chengrong Lu, Shutao Yin, Hongbo Hu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/6039769