Murine Gut Microbiome Association With APOE Alleles

Background: Since APOE alleles represent the most impactful genetic risk factors for Alzheimer's disease (AD), their differential mechanism(s) of action are under intense scrutiny. APOE4 is robustly associated with increased AD risk compared to the neutral APOE3 and protective APOE2. APOE allel...

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Bibliographic Details
Main Authors: Ishita J. Parikh, Janice L. Estus, Diana J. Zajac, Manasi Malik, Juan Maldonado Weng, Leon M. Tai, George E. Chlipala, Mary Jo LaDu, Stefan J. Green, Steven Estus
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00200/full