Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice.

Metabolic Effects of CX3CR1 Deficiency in Diet-Induced Obese Mice.

The fractalkine (CX3CL1-CX3CR1) chemokine system is associated with obesity-related inflammation and type 2 diabetes, but data on effects of Cx3cr1 deficiency on metabolic pathways is contradictory. We examined male C57BL/6 Cx3cr1-/- mice on chow and high-fat diet to determine the metabolic effects...

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Bibliographic Details
Main Authors: Rachana Shah, Sean M O'Neill, Christine Hinkle, Jennifer Caughey, Stephen Stephan, Emma Lynch, Kate Bermingham, Gina Lynch, Rexford S Ahima, Muredach P Reilly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4579121?pdf=render

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http://europepmc.org/articles/PMC4579121?pdf=render

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