Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment—a distinct inflammatory pattern for oligoarticular juvenile arthritis

Abstract Background Juvenile idiopathic arthritis (JIA) is an umbrella term of inflammatory joint diseases in children. Oligoarthritis is the most common form in the Western world, representing roughly 60% of all patients. Monocytes and macrophages play an important role in adult arthritides, but th...

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Bibliographic Details
Main Authors: Tobias Schmidt, Elisabet Berthold, Sabine Arve-Butler, Birgitta Gullstrand, Anki Mossberg, Fredrik Kahn, Anders A. Bengtsson, Bengt Månsson, Robin Kahn
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13075-020-02279-9