Simultaneous Measurement of Urinary Trimethylamine (TMA) and Trimethylamine <i>N</i>-Oxide (TMAO) by Liquid Chromatography–Mass Spectrometry
Trimethylamine (TMA) is a gut microbial metabolite—rendered by the enzymatic cleavage of nutrients containing a TMA moiety in their chemical structure. TMA can be oxidized as trimethylamine <i>N</i>-oxide (TMAO) catalyzed by hepatic flavin monooxygenases. Circulating TMAO has been demons...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/8/1862 |