GITR Promotes the Polarization of TFH-Like Cells in Helicobacter pylori-Positive Gastritis

Gastric CD4+T cells contribute to Helicobacter pylori (H. pylori)-induced gastritis by amplifying mucosal inflammation and exacerbating mucosal injuries. However, the pathogenic CD4+ T cell subset involved in gastritis and the potential regulators are still unclear. Here we identified an IL-21-produ...

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Bibliographic Details
Main Authors: Siqi Ming, Huan Yin, Xingyu Li, Sitang Gong, Guoliang Zhang, Yongjian Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.736269/full