A Compositional Model to Predict the Aggregated Isotope Distribution for Average DNA and RNA Oligonucleotides

A Compositional Model to Predict the Aggregated Isotope Distribution for Average DNA and RNA Oligonucleotides

Structural modifications of DNA and RNA molecules play a pivotal role in epigenetic and posttranscriptional regulation. To characterise these modifications, more and more MS and MS/MS- based tools for the analysis of nucleic acids are being developed. To identify an oligonucleotide in a mass spectru...

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Bibliographic Details
Main Authors: Annelies Agten, Piotr Prostko, Melvin Geubbelmans, Youzhong Liu, Thomas De Vijlder, Dirk Valkenborg
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Metabolites
Subjects:
DNA
RNA
oligonucleotide
prediction
isotope distribution
mass spectrometry
Online Access:https://www.mdpi.com/2218-1989/11/6/400

Internet

https://www.mdpi.com/2218-1989/11/6/400

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