Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine expansion in the Huntingtin protein which results in the selective degeneration of striatal medium spiny neurons (MSNs). Our group h...

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Bibliographic Details
Main Authors: Chen Xi, Wu Jun, Lvovskaya Svetlana, Herndon Emily, Supnet Charlene, Bezprozvanny Ilya
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:http://www.molecularneurodegeneration.com/content/6/1/81