Dantrolene is neuroprotective in Huntington's disease transgenic mouse model
<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine expansion in the Huntingtin protein which results in the selective degeneration of striatal medium spiny neurons (MSNs). Our group h...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-11-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://www.molecularneurodegeneration.com/content/6/1/81 |