A comparative approach to understanding tissue-specific expression of uncoupling protein 1 expression in adipose tissue

A comparative approach to understanding tissue-specific expression of uncoupling protein 1 expression in adipose tissue

The thermoregulatory function of brown adipose tissue (BAT) is due to the tissue-specific expression of uncoupling protein 1 (UCP1) which is thought to have evolved in early mammals. We report that a CpG island close to the UCP1 transcription start site is highly conserved in all 29 vertebrates exam...

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Bibliographic Details
Main Authors: Andrew eShore, Richard D Emes, Frank eWessely, Paul eKemp, Clemento eCillo, Maria eD'Armiento, Nigel eHoggard, Michael Anthony Lomax
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Genetics
Subjects:
Adipose Tissue, Brown
CpG Islands
Methylation
uncoupling protein 1
phylogenic analysis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00304/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00304/full

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