circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis

circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis

Meningitic Escherichia coli invasion of the host brain can lead to increased blood-brain barrier (BBB) permeability. Circular RNAs (circRNAs) are non-coding RNAs, highly abundant in the brain, that are widely involved in the pathological processes of central nervous system (CNS) disorders; however,...

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Bibliographic Details
Main Authors: Ruicheng Yang, Jiaqi Chen, Bojie Xu, Bo Yang, Jiyang Fu, Siyu Xiao, Chen Tan, Huanchun Chen, Xiangru Wang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
blood-brain barrier
brain microvascular endothelial cells
circ_2858
miR-93-5p
vascular endothelial growth factor A
permeability
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312030305X

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http://www.sciencedirect.com/science/article/pii/S216225312030305X

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