Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys.

Prophylaxis with high doses of neutralizing antibody typically offers protection against challenge with viruses producing acute infections. In this study, we have investigated the ability of the neutralizing human monoclonal antibody, KZ52, to protect against Ebola virus in rhesus macaques. This ant...

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Bibliographic Details
Main Authors: Wendelien B Oswald, Thomas W Geisbert, Kelly J Davis, Joan B Geisbert, Nancy J Sullivan, Peter B Jahrling, Paul W H I Parren, Dennis R Burton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1779296?pdf=render