EcSeg: Semantic Segmentation of Metaphase Images Containing Extrachromosomal DNA

Summary: Oncogene amplification is one of the most common drivers of genetic events in cancer, potently promoting tumor development, growth, and progression. The recent discovery that oncogene amplification commonly occurs on extrachromosomal DNA, driving intratumoral genetic heterogeneity and high...

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Bibliographic Details
Main Authors: Utkrisht Rajkumar, Kristen Turner, Jens Luebeck, Viraj Deshpande, Manmohan Chandraker, Paul Mischel, Vineet Bafna
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219304158