DV21 decreases excitability of cortical pyramidal neurons and acts in epilepsy

Abstract Epilepsy is one of the most common neurological disorders and the administration of antiepileptic drugs (AEDs) is the most common treatment. Although there are more than 15 AEDs available, a third of epilepsy patients remain refractory to available drugs, so novel effective drugs are needed...

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Bibliographic Details
Main Authors: Min Xu, Peng Sun, Ying Zhang, Ci-Hang Yang, Xin Wei, Xiao-Xia Ma, Chong-Ren Yang, Kun-Ming Ni, Ying-Jun Zhang, Xiao-Ming Li
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01734-z