Glucose restriction drives spatial reorganization of mevalonate metabolism

Glucose restriction drives spatial reorganization of mevalonate metabolism

Eukaryotes compartmentalize metabolic pathways into sub-cellular domains, but the role of inter-organelle contacts in organizing metabolic reactions remains poorly understood. Here, we show that in response to acute glucose restriction (AGR) yeast undergo metabolic remodeling of their mevalonate pat...

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Bibliographic Details
Main Authors: Sean Rogers, Hanaa Hariri, N Ezgi Wood, Natalie Ortiz Speer, W Mike Henne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
lipid droplet
mevalonate
nucleus-vacuole junction
sterol-ester
HMG-CoA Reductase
Online Access:https://elifesciences.org/articles/62591

Internet

https://elifesciences.org/articles/62591

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