GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain

GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain

Toxoplasma gondii causes infections in a wide range of intermediate hosts and remains a threatening disease worldwide because of the lack of effective drugs and vaccines. Dense granule protein 24 (GRA24) is a novel essential virulence factor that is transferred into the nucleus of host cells from th...

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Bibliographic Details
Main Authors: Bin Zheng, Di Lou, Jianzu Ding, Xunhui Zhuo, Haojie Ding, Qingming Kong, Shaohong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
immunization
DNA vaccine
GRA24
Th1/Th2 cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00418/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00418/full

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