Uridine Diphosphate Promotes Rheumatoid Arthritis Through P2Y6 Activation

BACKGROUND: Uridine diphosphate (UDP) is an extracellular nucleotide signaling molecule implicated in diverse biological processes via specific activation of pyrimidinergic receptor P2Y, G Protein-Coupled, 6 (P2Y6). There is very little knowledge about the function and mechanism of UDP in rheumatoid...

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Bibliographic Details
Main Authors: Hongxing Wang, Hui Wu, Kehua Fang, Xiaotian Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.658511/full